SVP, Head of Data & Analytics (DnA)
At 2seventy, it's all about time – how you use your time to do meaningful work that matters, who you choose to spend your time with, and how we can give more time to our patients. When you join us, you are so much more than a number – we invite you to bring all of you and become part of a community where we believe we are better 2gether. Are you ready to re-think the (im)possible? Not only are we ready – we are doing it. The time is NOW.
We think differently about data. Our data sits at the very heart of what we do at 2seventy bio, where we believe in the power of autologous T cell therapies to cure cancer. This modality presents a unique opportunity to connect data from the clinic, our manufacturing processes, and our research labs to derive deep insights that will allow us to continuously improve our therapies and give our patients more time. It's why we've created the ONE DATA TEAM bringing together classically disconnected data functions into a single Data and Analytics group. This team combines the Clinical (statistical programming, biostats, clinical data management), Research (data science analytics and engineering), and Manufacturing (process data systems and statistics) data functions into a single integrated department. Our goal is to eliminate data silos, consolidate and deepen our data and analytics expertise, maximize efficiency, and enable data-driven decisions to further our research and clinical development. Whether deriving deep insights from our clinical studies, enabling research to move at the speed of thought, or keeping our finger on the pulse of our manufacturing operations to ensure peak performance, at 2Seventy bio we are driven by a desire to improve human health through data. Come work with a group that is passionate about data and loves rising to the challenge!
About the Role:
- Lead a diverse group of data scientists, data engineers, biostatisticians, and experts in clinical data management, statistical programming and operations that are dedicated to integrating and analyzing the Company's data across research, clinical, and CMC/manufacturing with the aim of designing and delivering transformative therapies to cancer patients.
- Create a vision for and champion the digital transformation of 2Seventy bio's data ecosystems by fostering a strong relationship with partner functions (IT, Quality, etc).
- Guide and support the development of biometrics capabilities, balancing advanced analytical strategies and statistical methodologies, operations, and innovation in support of clinical trials from study design through submission and lifecycle management.
- Guide and support the development of operational infrastructure for clinical data management, data standards, data sharing, and overall data governance.
- Set strategy for the function, balancing delivery of near-term goals and longer-term implementation of enterprise data infrastructure inclusive of data standards and governance.
- Build, develop, and mentor an outstanding team that successfully integrates data & analytics across the research, manufacturing, and clinical functions at 2Seventy.
- Participate in research leadership team to shape the culture and strategy of the organization.
- In partnership with IT leadership, develop an architecture and capabilities roadmap to enable and support emerging technologies and methodologies, (AI/ML, CI/CD, etc)
About you:
- 15+ years' experience in biotech or pharma delivering impactful analyses in cancer R&D, including translational research studies going from "bench to bedside".
- PhD or advanced degree in bioinformatics, biostatistics, computer science.
- 5+ years' leading cross-functional teams with a demonstrated ability to recruit outstanding talent and develop them.
- 2+ years' experience in the cancer gene therapy space.
- An inclusive leader, with experience creating an environment where all colleagues can develop and that enables their best performance
- History of building and leading a best-in-class data & analytics organization.
- An experienced leader who can engage with scientific and medical thought leaders and leverage strategic insight and operational excellence.
- Solid understanding of clinical trial process from research transition through submission.
- Working knowledge of current and future industry trends including AI/ML, digital technologies, RWD, etc.
- Knowledge of best practices and regulatory requirements for management and governance of data in pharmaceutical development.
- Experience collaborating across R&D, CMC, IT, and Quality with solid understanding of interactions between functions.
- Excellent problem solving, critical thinking, and communication skills with the ability to understand, communicate, and present technical and complicated solutions in a clear and simple manner to stakeholders.
- Familiarity or knowledge of industry data standards (e.g., CDISC, SDTM).
- Experience supporting submissions to health authorities and a thorough understanding of applicable regulatory requirements and guidance.
- Experience with applying omics and translational data analyses to support the discovery and development of novel therapies.
- Looking to solve difficult, messy problems like developing cell therapies for cancer—it's hard!
- Ability to communicate above and below level in a way that fosters relationship building, including cross-functional teams, and external relationships with vendors
- Successfully worked in a collaborative team environment where results are achieved through influence and incorporating multiple points of view
- Excellent attention to detail, project and time management skills, and the ability to manage multiple priorities
- Embraces and models our core values—re-think, have heart, better 2gether, time is now